High value partner to move project faster

Flamma was started in 1950 by Dr. Marco Maria Negrisoli and his wife, Dr. Edmea Kullmann, a chemist. Together they infused into FLAMMA not only their passion for chemistry but also, above all else, very strong principles of ethics and great humanity. Many years have passed since our humble beginnings. The world and our society have changed dramatically, yet these principles remain unaltered and are still the cornerstone of FLAMMA’s activity and development.

The name “Flamma” comes from “Fabbrica Lombarda Ammino Acidi” which means that a Factory in the Lombarda region of Italy making Amino Acids.

Marco Negrisoli decided to solve a problem that existed at the time. There was nobody serving the Italian industry and Western Europe with amino acids. The business quickly grew and soon customers were asking Flamma if they could make specialty amino acids. Flamma began making custom amino acids and expanded to where they outgrew their location in Bergamo necessitating a search for a larger facility.

Gian Paolo Negrisoli, son of Marco, was now leading the company and decided to move to an industrial park just outside of Bergamo. Chignolo d’Isola was where Flamma has been since 1996. The company continued to grow with the addition of an API production plant and pilot plant. As one of the newest pharmaceutical facilities in Italy, Flamma continued to move toward FDA inspection and in 2009, the Chignolo facility was inspected by the US FDA.

Gian Paolo did not stop there as he saw the value of China and had already began plans to work in China. Initially, Flamma established a joint partnership called Gongan Flamma Biochemicals but soon learned that they needed to have full control of their own business to be successful. Thus, Flamma China began first in Shanghai in 2005 and eventually moved to Dalian where Flamma has been active since 2008.

Meanwhile, Flamma opened sales offices in 2006 in Paris and 2010 in Boston to support the growth of the company. Flamma also expanded with the acquisition of Flamma Isso allowing Flamma to grow within Italy and double its capacity to 250 m3.

Since 2010, Flamma has grown from 2 sites, 120 m3 of capacity and 125 team members to its current state of 4 sites, 450 m3 and over 550 team members. The addition of cGMP facilities at Flamma Honkai in 2017 continues to show the industry that Flamma is listens to its customer base. This ability to listen led to Flamma acquiring a facility in the USA (in the Philadelphia area) in late 2019.

Flamma continues to constantly dialogue with its customers to provide them with what they desire in a CDMO. Providing an integrated, stable supply chain is just part of what Flamma does.

100% Family owned and run since 1950. Flamma is here for you and your manufacturing needs. Flamma provides a fully integrated supply chain which is only possible since Flamma is using Italy, China & the USA together. Flamma Honkai provides the security of working in China due to our consistently present Italian management & oversight. It is like having an Italian facility in China. Having the ability to take on smaller volume projects at Flamma USA allows customers to grow the project by taking advantage of Flamma’s other resources in Italy and China.

 

1950

1950

Established in Bergamo, by Dr. Marco Maria Negrisoli Core Business: Amino Acids and Derivatives & APIs

1996

1996

Relocation to current headquarters in Chignolo d’Isola (Bergamo) after the construction of the manufacturing plant.

1998

1998

Capacity increased by the expansion of the production plant

2001

2001

New pilot plant begins operations along with the opening of new R&D and QC labs at the Chignolo facility

2001

2001

Flamma begins operations in China

2005

2005

Shanghai Flamma Bioscience Co. Ltd, facility establishes R&D labs in China

2006

2006

Flamma France (Paris) office established

2008

2008

A new API Manufacturing Unit in Chignolo is established

2008

2008

Relocation of R&D labs from Shanghai to Dalian Flamma Bioscience Co. Ltd. in China

2009

2009

Chignolo site successfully inspected by the US FDA along with the establishment of Flamma LLC USA (Boston)

2011

2011

Expansion of production plant in Dalian

2012

2012

Flamma Isso is acquired and doubles Flamma’s production capacity in Italy

2013

2013

Dalian Honkai production plant revamped and upgraded to mimic Flamma Italy

2014

2014

FDA and AIFA inspections of Chignolo, Italy site

2015

2015

New API warehouse opened in Chignolo

2016

2016

Successful FDA inspection at Chignolo

2017

2017

Dalian Honkai renamed Flamma Honkai (Dalian) Pharmaceutical Development Co., Ltd.. Also a new cGMP workshop was added as well as a new R&D building

2019

2019

Flamma-delphia is acquired giving Flamma a cGMP pilot plant and labs in the USA