glp-1 therapy hydration effects weight loss Side Effects: When to Call a Doctor UC Davis Health examines systemic

This oligomerization triggers the autoproteolytic maturation of caspase-1, activating its inflammatory caspase function

But that qualifier the ones with actual evidence is doing a lot of heavy lifting in that sentence

ITT, Intention-to-treat

Monitor for any unusual symptoms

While the 2024 guidelines already recommended glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for weight loss due to their proven efficacy in reducing body weight and improving glycemic control, the 2025 update broadens their scope of use for their multifaceted benefits in diabetes management, including weight loss, kidney disease, and metabolic dysfunction-associated steatotic liver disease (MASLD)/metabolic-associated steatohepatitis (MASH) [11, 12]