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In a recent preclinical study (Vargiu et al., 2021) it has been shown that chronic consumption of the ED Red Bull during adolescence increases dopamine in the nucleus accumbens (NAcb) shell dopamine via a non-adaptive mechanism, as observed with drugs of abuse

Morris MR, Gentle D, Abdulrahman M, Maina EN, Gupta K, Banks RE, Wiesener MS, Kishida T, Yao M, Teh B, Latif F, Maher ER (June 2005)

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This distinction is important because pulse timing, amplitude, and inter-burst recovery intervals each influence receptor responsiveness and downstream signaling behavior