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Iron chelator deferoxamine protects human neuroblastoma cell line SH-SY5Y from 6-Hydroxydopamine-induced apoptosis and autophagy dysfunction
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MYC is one such oncogene with varying metabolic requirements, and its role in breast cancer is well established
The mutants SnCE1 fl C256A and SnCE1 fl Y212A show a similar localization, suggesting a functional deSUMOylase activity not being essential for its localization to the ER
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