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Rat tissue sections were pretreated for 15 min with HIER at 95 C in ER2 (Leica) followed by a 15-min protease treatment and then hybridized with rat-specific probes to detect mRNA transcripts for CALCR (477798), PRLH (1301288-C2) and GLP1R (315228-C3

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The intention-to-treat analysis had some concerns of bias in 36% of the studies

Plaintiffs in current lawsuits allege that Eli Lilly and Company failed to adequately warn patients and healthcare providers about the severity, persistence, and potential long-term consequences of these gastrointestinal risks

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