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Complete blood counts and comprehensive metabolic panels at baseline and periodic intervals could detect any unexpected hematological or organ toxicity, though preclinical data suggests low risk

Reconstitution of ava 2 C or L was carried out at 37 C for 1 h in a reaction mixture containing 100 mM HEPESKOH (pH 8.6), 50 mM KCl, 2 mM ATP, 2 mM DTT, 10 mM 5-AVA hydrochloride or l-lysine monohydrochloride (FUJIFILM Wako Pure Chemical), 1 g transcribed tRNA and 1.5 M E

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