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Refrigeration isn't just "better" - it can extend usable life by 3-10x depending on the form

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RNA concentration and fragment sizes were evaluated for QC using BioAnalyzer or Agilent TapeStation, then library prep performed and sequenced using Ilumina 97 HiSeq4000 by the Yale Stem Cell Center Genomics Core

Edwall, D., Schalling, M., Jennische, E

Discussion In the present study we show that exogenous melatonin on the protects against the reduction during the aging of mice as indicated by litter size