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In clinical studies, patients receiving clozapine plus adjunctive glycine experienced reduced antipsychotic benefit-likely owing to altered NMDA-receptor signaling

[54] Medical uses [edit] Replacement therapy [edit] GH is used as replacement therapy in adults with GH deficiency of either childhood-onset or adult-onset (usually as a result of an acquired pituitary tumor)

A 2022 scientific review published in the National Library of Medicine confirmed that nasal delivery of therapeutic peptides is a non-invasive and fast-acting method that can effectively bypass the blood-brain barrier while minimising systemic exposure

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Research suggests DSIP may modulate stress hormone levels, including potential effects on cortisol and ACTH