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Usual Maintenance Dosage 0.5 mg to 2 mg SC once a week , based on individual response and blood sugar control

In general, a urine flow rate of less than 1 L per day increases the risk of stone formation (Curhan 2012), and guidelines for people with a history of kidney stones include the recommendation to maintain their urine output above 2 L per day (Antonelli 2015)

This can lead to rapid destruction of red blood cells (hemolysis) and the formation of Heinz bodies (denatured hemoglobin aggregates) in these patients