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The liver-specific insulin receptor knockout (LIRKO) mouse model suggests that the insulin signalling is essential for the regulation of glucose homoeostasis in the liver and maintenance of normal liver function [84]

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Lyophilization helps preserve a peptides integrity and activity, making it easier to handle, store, and transport [6]

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Kovacic P, Somanathan R: Cell signaling and receptors in toxicity of advanced glycation end products (AGEs): alpha-dicarbonyls, radicals, oxidative stress and antioxidants