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With the full Phase 1 maintenance trial data, likely reported in Q326, this will provide additional de-risking (if data is positive), allowing a potential re-sizing, as the Phase 3 trial data grows closer

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In phase I, enzymes such as Cytochrome P450 oxidases introduce reactive or polar groups into xenobiotics

Many Americans (79%) said they believe GLP-1 weight loss is judged more harshly than losing weight through diet and exercise alone