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Similarly, gallbladder issues like gallstones can arise

Quantitative endpoints, such as MRI-PDFF and histology, can capture subtle yet clinically meaningful changes, whereas ALT/AST and ultrasonography may miss early metabolic improvements

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In the Liraglutide Efficacy and Action in Diabetes (LEAD) programme (61), a total of 154 patients with T2D within the LEAD-2 trial participated in a sub-study to assess liver fat content by the liver-to-spleen attenuation ratio at a computer tomography (CT) scan