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A consistent model goes with ligation leading to vessel injury, exposure of tissue factors, stasis, thrombosis, hemodynamic changes, arterial hypotension, and in particular, venous hypertension, which approximates values over 20 mm Hg in the inferior caval vein, thereby being roughly four times higher than those in normal rats

Acta Neurol Scand 114:17 Raskind JY, El-Chaar GM (2000) The role of carnitine supplementation during valproic acid therapy