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First-line treatment in most guidelines while homeopathic approaches like Conium Maculatum for ED are sometimes explored as adjuncts

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NICE-recommended options include orlistat (available on prescription or at a lower dose over the counter), and GLP-1 receptor agonists such as semaglutide (Wegovy) or liraglutide (Saxenda) for those who meet specialist service eligibility criteria

NICE guidance (NG28) on the management of type 2 diabetes recommends SGLT2 inhibitors with proven cardiovascular benefit as the preferred option for patients with established atherosclerotic cardiovascular disease

The remaining 30% of NMOSD are caused by MOG auto-antibodies that target and injure oligodendrocytes