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Effect of MEDI7219 oral tablets on weight and glucose control in a dog model of obesity and insulin resistance Eighteen male beagle dogs weighing an average of 10.9 0.3 kg were housed at Charles River Laboratories (Worcester, MA, USA) and received two cups of 5A4J HFHF canine diet daily (20.5% protein, 52.9% fat, 26.6% carbohydrate, 18.9% fructose

The effect was particularly strong at low glucose concentrations

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One patch at a time, up to 8 hours