This basal medium was then augmented with a specific cocktail of small molecules: 3 M or 1 M CHIR99021 (CHIR), IDE1, 2 M Ly294002 (Ly), and 0.75 M PD0332991 (PD)
The Journal of cell biology, 1994, 125(4): 929- 943
That being said, Dihexa was administered to the rats in doses of 1.44 mg/kg of 2.88 mg/kg in order to see how levels of AngIV changed in response to the nootropic compound
GHK-Cu also suppresses the over expression of transforming growth factor-beta (TGF-)1 that has been noted in patients with hereditary hair loss, leading to hair shaft thickening and elongation
Animal studies show it reduces inflammation in colitis models, heals intestinal anastomoses (surgical connections), reverses intestinal perforations, and protects the gut lining from NSAID damage