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Altered expression of redox-responsive proteins and translocation of transcription factor NFB-p65, accompanied by activation of AMP-activated protein kinase (AMPK), SIRT-1, Glut-4, and PPAR- suggests the induction of antioxidant defense responses and increased energy metabolism in GK diabetic rats after exercise

Increased export of GSH can be a part of GBM cells strategy to protect themselves from oxidative damage induced by this therapeutic approach, mitigating the harmful effects of ROS in the surrounding TME

Along with a proton gradient force, the ABC transporters have also been reported in sequestration of flavonoids into the vacuole (Yazaki, 2005

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4.8.1.2 BM-MSCs BM-MSCs could be obtained from the bone marrow through isolation of the mononuclear cell