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Quick Takeaways BPC-157 is a mechanistically compelling peptide with strong animal data on healing, inflammation, and neuroprotection Both injectable and oral forms of BPC_157 have well-established real-world utility, and are the only proven paths for experiencing the real healing benefits of BPC-157 Nasal spray bioavailability for BPC-157 is poor, a consistent observation of experienced clinicians and self-experimenters No human clinical trials exist for BPC-157 in any delivery format, including the nasal spray Intranasal delivery is theoretically interesting for CNS access, but specifically remains unvalidated when it comes to BPC-157 What Is BPC-157

Chemical and structural modifications of RNAi therapeutics

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Substantial evidence has been provided that IIS is an evolutionarily conserved pathway that regulates lifespan across many species like flies, worms, and mice [36]

Natelson BH, Pareja J, Policastro T, Cheu J, Ellis SP, Findley TW