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These agents have been supported by important clinical trials, including Satiety and Clinical Adipose Liraglutide Evidence (SCALE), Semaglutide Treatment Effect in People with Obesity (STEP) program trials, and Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1) (44)

The expectation is to improve the effectiveness of treatments while minimizing their adverse effects by reducing the concentration of each agent or the intensity of the procedures

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