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All participants experienced reductions in weight, waist circumference, blood pressure, lipid levels, and glycemic markers during the initial 36 weeks of tirzepatide therapy

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The researchers emphasize that more research is needed to determine whether similar changes to organ size occur in humans -- and whether those changes come with any risks

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Glucagon-like peptide-1 analog therapy in rare genetic diseases: monogenic obesity, monogenic diabetes, and spinal muscular atrophy