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1.3.1 Transport proteins in the kidneys In the renal domain, numerous SLC transporter proteins are present, including organic anion transporters (OAT 1/2/3/4), organic cation transporters (OCT 2/3), organic anion-transporting polypeptides (OATP 4C 1), multidrug and toxin extrusion proteins (MATE 1/2-K), urate anion exchanger protein (URAT1), and organic cation/carnitine transporters (OCTN 1/2), among others

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Zero-order kinetics make dose titration challenging

Along with its role in lowering blood glucose levels, LIXI has many other functions, such as cardiovascular benefits, delaying gastric emptying, protective effect on pancreatic beta-cells, and increased insulin mRNA expression and hormone secretion (65)

What Is Gastric Sleeve/VSG