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However, outcomes vary depending on individual physiology, adherence, and medical factors
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2014;41(7):45968 Lin J, Fung TT, Hu FB, Curhan GC
Dosing frequency Once daily: 200-300 mcg, typically before bed Simplest protocol Aligns with natural nighttime GH surge Good for anti-aging and general wellness Twice daily (preferred for most goals): 100-150 mcg morning (fasted or post-workout) 100-150 mcg before bed Better mimics natural pulsatile release Superior for muscle growth and fat loss Three times daily (advanced): Used by some athletes and bodybuilders Morning, post-workout, and bedtime 100 mcg per dose Requires more commitment Timing considerations Best times to inject: Before bed: Aligns with natural GH peak during sleep
doi:10.1016/j.jad.2012.05.022 Gibson SA, Korade , Shelton RC (2012) Oxidative stress and glutathione response in tissue cultures from persons with major depression
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