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Tirzepatide has been associated with modest increases in resting heart rate (mean increase of 24 bpm in clinical trials), though the mechanism is unclear

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L-carnitine is an amino acid that helps fuel the mitochondria (engines) of the cells. Research has shown L-carnitine supplementation had a dramatically increase in resting energy expenditure (REE) and fat-burning capacity than non users. In a review of nine studies of people with obesity, researchers found that participants taking L-carnitine lost about 2.9 more pounds (1.3 more kilograms) than those who didnt. The effective dose starts at approx 2g with 3g being more beneficial

10.1038/ajg.2013.451 5 AtreyaR.MudterJ.FinottoS.MllbergJ.JostockT.WirtzS.et al (2000)

The warmed milk is then poured over the espresso and stirred