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Dehydration: Common with illnesses involving fever, vomiting, or diarrhea, dehydration can reduce blood volume and affect kidney function, impacting medication clearance

These medications work by mimicking incretin hormones, enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways

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It remains an unlicensed investigational compound, with Phase 3 clinical trials ongoing