Think beyond particle cytotoxicity: when self-cellular components released after immunogenic cell death explain chronic disease development
The action of withanolides, steroidal lactone triterpenoids, which share chemical structural similarities with testosterone and may therefore mimic the effects of male steroidal hormones, is another way that ashwagandha affects the reproductive system and fecundity [203]
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Looking forward, the integration of complementary technologies bulk, single-cell, spatial, and multi-omics together with computational modeling will be critical for connecting molecular-level discoveries in MuSC biology to systemic physiology and, eventually, to translational interventions for muscle aging
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