Riboflavin (vitamin B2) and vitamin D are additional cofactors that may support glutathione recycling and endogenous antioxidant production
Langan D, Higgins JPT, Simmonds M
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A strong letter of medical necessity should include: your BMI history over at least 12 months, documentation of weight-related comorbidities (hypertension, type 2 diabetes or prediabetes, dyslipidemia, sleep apnea), prior weight-loss attempts and their outcomes, the specific clinical trial data supporting the requested medication, and a statement that the medication is medically necessary (not cosmetic)
It also makes several recommendations for systemic reforms to the patent system to counter the influence of financialization that incentivizes patent abuse, as well as healthcare policies to address these inequities and promote affordable access to these life-changing treatments.