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Magn Reson Med.

The FDA sent over 50 warning letters in September 2025 to companies doing it anyway

The marginal change in TUNEL staining somewhat mirrors the changes in mitophagy markers in the females brain, suggesting the mitophagy regulation may play a critical role in cell integrity

However, several interaction points warrant careful monitoring: hypoglycemia risk in patients on concurrent diabetes medications, changes in lipid levels, potential impacts on blood pressure, and rare but serious pancreatitis or gallbladder complications

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