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The total cell count, morphology, and the gene expression profile of iEANs in the duodenum, ileum, and colonic myenteric plexus varies significantly, with a higher neuronal count in specific-pathogen-free mice compared to germ-free animals (Matheis et al., 2020)

Accessed May 6, 2026.

In patients with T2D, human amylin is known to accumulate in the pancreatic islets of Langerhans, forming oligomer aggregates that contribute to beta-cell damage in T2D

The compound's pro-angiogenic effects improve vascular supply to muscle tissue, supporting the nutrient delivery necessary for repair and rebuilding