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In the context of food motivation, GLP-1 receptor agonists reduce food intake, conditioned place preference for previously preferred chocolate pellets, and progressive ratio responding for sucrose pellets (Raun et al., 2007

The greatest concern is that while in the short-term the program could provide health benefits to those who need help with weight management, in the long-term those same problems could return if there is a failure to extend the program past its current end date, Beene said

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At the same time, GLP-1 suppresses the release of glucagon, a hormone responsible for raising blood sugar levels

Mice with loxP sites flanking the fifth TR exon (TR Floxed mice), developed by Shanghai Model Organism Center, Inc., were fertile and appeared indistinguishable from TR +/+ mice