Research protocols use 0.1-0.3 mg per dose, administered subcutaneously in the evening
Compared to MOTS-c, which targets mitochondrial energy metabolism through a completely separate cellular mechanism and requires only 4 injections per cycle, Epithalon runs for 10 consecutive nightly doses and focuses on cellular renewal and the aging process itself
The principle behind the leaky gut theory is that endogenous (e.g., psychological stress, intestinal inflammation) and exogenous factors (e.g., diet, alcohol intake) can increase intestinal permeability, allowing the entrance of food antigens, commensal or pathogenic bacteria and bacterial components into the lamina propria and later on into the systemic circulation, provoking the systemic inflammation described in different disease conditions
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This is because aging adults often develop problems with the acids and stomach enzymes needed to process the vitamin