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These molecules share structural similarities with major histocompatibility complex class I (MHC-I) proteins [159]

Cryo-EM data acquisition The concentrated sample (3.5 L) was applied to glow-discharged holey carbon grids (Quantifoil R1.2/1.3, 300 mesh), and subsequently vitrified using a Vitrobot Mark IV (ThermoFisher Scientific) set at 100% humidity and 4C

Short periods of mild temperature variation may not harm the medication, but its best to cool it as soon as possible

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This ensures the surface where the needle will enter is completely sterile