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However, H 2 O 2 can also lead to the production of the more damaging oxygen radical, OH , which can initiate a cascade of cellular injury through peroxidation of lipid, protein and DNA [24]

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10.1016/j.jsps.2019.05.004 Saudi Pharm

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Additionally, the study found that weight gain after stopping was strongly associated with reinitiation, suggesting that many patients may need long-term therapy to maintain weight loss. The researchers concluded more studies are needed to explore how long-term health outcomes are tied to GLP-1 discontinuation and to assess how interventions financial barriers to the drugs and mitigate adverse events